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Targanta to develop diarrhea treatment

Targanta Therapeutics Corp. is beginning efforts to develop a new version of its lead antibiotic that would treat an infection that causes severe diarrhea, even as it awaits federal regulatory approval for the original drug.

The Cambridge, Mass. company (Nasdaq: TARG) said on Monday that it had launched a program designed to create an oral version of its antibiotic oritavancin that would treat a form of bacteria that causes severe diarrhea and costs the U.S. health care system more than $1.1 billion annually.

The particular bacteria -- C. Difficile -- is also a high cause of death in elderly patients in the hospital.

Targanta expects to begin human clinical trials for the oral version of oritavancin in early 2009. The company is already seeking regulatory approval for an intravenous version of the drug, which is designed to treat skin infections.


Leading Online Retailer of Physician Grade Skin Care Products Assumes New Store Name

Caliderma announced today that it has begun operating under the name iderma. Iderma is an online retailer of physician grade skin care products located on the internet at www.iderma.com.

Austin, TX (PRWEB) April 17, 2008 -- Caliderma announced today that it has begun operating under the new name of iderma. Iderma is an online retailer of physician grade skin care products located on the internet at www.iderma.com.

Caliderma began operations in 2005 and has quickly grown to become one of the leading online retailers of brands such as SkinMedica, iS Clinical, Remergent and RevaleSkin. In addition to items such as anti-aging products and sunscreens, the store also sells mineral makeup lines including GloMinerals, Jane Iredale and Susan Posnick Cosmetics.

Each day a person's skin is exposed to damaging environmental elements like sun and pollutants that can cause premature wrinkling and aging.


Make Cosmetic Purchasing Easier - DaVinci Cosmetics Helps You

DaVinci Cosmetics holds a distinction for possessing and marketing a very wide range of world class cosmetics. These include mineral makeup, face powder, blush, bronzer and many other products pertaining to skin care.

Los Angeles, CA (PRWEB) April 18, 2008 -- This is good news for all the people who have made makeup an integral component of their daily life. DaVinci Cosmetics, a very popular and renowned cosmetics brand, has come up with a more customer friendly scheme of selling its products through its new website http://www.adavinci.com.

The sales records of the products from this company are a proof of its popularity among the masses. The company believes in advertising its products at the right places in the right way to boost sales. The idea of coming up with a website for easier and effective cosmetics' shopping is another huge step taken by the company towards boosting its sale.


ValleyCats Release 2008 Promotional Calendar

TROY, N.Y. - The Tri-City ValleyCats, last year's recipient of the New York-Penn League's Larry MacPhail Award for the most outstanding promotional work throughout the season, have released their 2008 Promotional calendar. The new lineup features even more excitement, highlighted by 14 spectacular fireworks shows, a Tri-City Mayor's Bobblehead Series, Going Green Night and the 2008 National Grid New York-Penn League All-Star Game.

The ValleyCats kick off the season on Friday, June 20 against the Oneonta Tigers. All fans in attendance will receive a ValleyCats 2008 Schedule Magnet presented by Garelick Farms.

The Post-Game Fireworks Shows, return on Friday, June 27 for the first of an all-time ValleyCats record 14 shows. Celebrate the Fourth of July all week with Independence Week Fireworks, a three-day fireworks extravaganza on July 2nd, 3rd and 4th.


Scholars Address Islam And Democracy

Islam is more than a religion - it's a way of life, adherents believe.A cornerstone of the faith is shariah, or Quranic law. It's seen as the ultimate frame of reference, governing everything from permissible food to marriage and divorce.Most of the world's Muslim nations are ruled by military strongmen or kings. A recent push toward democratization has been accompanied by regime change and war.As Muslims struggle to take their place in an increasingly global community, they must address some big questions: Is separation of church and state possible? What would an Islamic version of democracy look like? Is there a peaceful means to get there?Two scholars tackled the questions at a forum on Islam and Democracy at the University of Arkansas on April 11. Sponsored by the Al-Islam (The Peace) Students Association and the UA Multicultural Center, the forum was one of a series hosted by the student organization to educate the community about Islam.Najib Ghadbian, associate professor of political science and Middle East studies at UA, laid the framework for understanding the relationship between democracy and Islam.


A Large Open Label, Non-Comparative, Phase III Study Of The Multi-Targeted Kinase Inhibitor Sorafenib In European ...

UroToday.com - Dr. Verzoni presented a trial to collect safety and efficacy data on sorafenib from a large and broad study population reflecting clinical practice. This nonrandomized, open-label study included male and female patients, aged ≥18, with an ECOG PS 0 2 and a life expectancy >2 months. Patients had to be unsuitable for or have failed prior cytokine therapy. Controlled, asymptomatic brain metastases were allowed. Patients received continuous therapy with sorafenib 400 mg twice daily until disease progression, intolerable toxicity, or withdrawal of consent. Dose increases were not permitted. Recruitment was planned to continue until regulatory approval of sorafenib for advanced RCC. Study assessments were conducted at baseline and then monthly. Adverse events were graded according to NCI CTCAE v 3.0 criteria.


Yes it's politically incorrect but race matters

American Presidential elections have been compared with reality TV series or game shows, in which a gaggle of jumped-up nonentities aspiring to be celebrities are ritually humiliated in public and offered entertaining opportunities to self-destruct, until only one survivor remains. But this time round, a much more elevated analogy is sadly apposite.

The 2008 US election has all the makings of a Greek tragedy, in which noble heroes and heroines are forced to follow a course to catastrophe, divinely preordained as punishment for sins and blunders committed by their forefathers in the dim and distant past. In acting out their ineluctable doom, the eloquent protagonists do not just destroy themselves but also their cities, their nations and even their entire civilisations.

If this description sounds too grandiose, consider yesterday's results from the Pennsylvania primary.


 
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